[Selective inhibition of pyruvate dehydrogenase in the liver and heart of mice by triphosphate esters of thiochrome and tetrahydrothiamine].

In experiments with white mice it was shown that in contrast to hydroxythiamine and other known vitamin B1 antagonists, triphosphate esters of thiochrome and tetrahydrothiamine possess a selective anticoenzyme activity with respect to the only one of the thiamine pyrophosphate-dependent enzymes, i.e. pyruvate dehydrogenase.