Noble R C, Shand J H
Biol Neonate. 1983;44(1):10-20. doi: 10.1159/000241689.
Fetal plasma contained significantly lower amounts of lipoproteins than the mother. In both mother and fetus, high density lipoprotein (HDL) was the major fraction. Very low density lipoprotein (VLDL) accounted for 12% of total plasma lipid in the mother but only 4% in the fetus. Maternal and fetal plasmas showed similar distributions of lipids in their HDL and low density lipoprotein (LDL) with cholesteryl esters comprising the major lipid of both and LDL having a higher level of triglycerides and lower level of phospholipids than HDL. Low levels of triglycerides were present in fetal VLDL. There were pronounced increases in levels of unsaturated fatty acids with increasing lipoprotein density. In the mother, levels of linoleic acid increased and in the fetus palmitoleic and oleic acids increased. The major saturated fatty acids in the fetal lipoproteins was palmitic acid and in the maternal lipoproteins stearic acid. In contrast to the mother, LDL and HDL of the fetus showed similar fatty acid compositions.
胎儿血浆中的脂蛋白含量明显低于母体。在母体和胎儿中，高密度脂蛋白（HDL）都是主要成分。极低密度脂蛋白（VLDL）占母体血浆总脂质的12%，但在胎儿中仅占4%。母体和胎儿血浆中HDL和低密度脂蛋白（LDL）的脂质分布相似，胆固醇酯是两者的主要脂质，且LDL的甘油三酯水平高于HDL，磷脂水平低于HDL。胎儿VLDL中的甘油三酯水平较低。随着脂蛋白密度的增加，不饱和脂肪酸水平显著升高。在母体中，亚油酸水平升高，在胎儿中，棕榈油酸和油酸水平升高。胎儿脂蛋白中的主要饱和脂肪酸是棕榈酸，母体脂蛋白中的是硬脂酸。与母体不同，胎儿的LDL和HDL显示出相似的脂肪酸组成。
