绵羊全肾切除术效果的研究。
Studies on the effects of total nephrectomy in sheep.
作者信息
Singh J, Singh A P, Peshin P K, Singh M, Sharma S K
出版信息
Can J Comp Med. 1983 Apr;47(2):217-21.
Effects of total nephrectomy were studied in six sheep. There was no marked deterioration in the clinical condition of the animals except anorexia and reduced water intake. Three sheep survived the period of observation of 120 hours when they were euthanized. One animal suddenly died at each of 76, 80 and 100 hours. Progressive increase of blood urea nitrogen concentration was accompanied by severe metabolic acidosis in the later stages. Plasma creatinine rose significantly but the change was not marked. Plasma inorganic phosphorous and calcium decreased significantly. Unaffected plasma sodium levels were accompanied by hyperkalemia and hypochloremia. Plasma total proteins and albumin decreased significantly in the later stages. Results showed markedly different responses to total nephrectomy in sheep as compared to changes reported in cattle and nonruminants.
对六只绵羊进行了全肾切除术的效果研究。除了食欲不振和饮水量减少外，动物的临床状况没有明显恶化。三只绵羊在120小时的观察期内存活下来，之后实施了安乐死。在76小时、80小时和100小时时各有一只动物突然死亡。后期血尿素氮浓度逐渐升高，并伴有严重的代谢性酸中毒。血浆肌酐显著升高，但变化不明显。血浆无机磷和钙显著降低。血浆钠水平未受影响，但伴有高钾血症和低氯血症。后期血浆总蛋白和白蛋白显著降低。结果表明，与牛和非反刍动物报道的变化相比，绵羊对全肾切除术的反应明显不同。
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