Hamaker R C, Singer M I, Shockley W W, Pugh N, Shidnia H
Cancer. 1983 Sep 15;52(6):1017-21. doi: 10.1002/1097-0142(19830915)52:6<1017::aid-cncr2820520615>3.0.co;2-7.
The cosmetic and functional disability associated with mandibular resection has been a major problem to the patient with direct invasion of the mandible by oral cancer. Marginal resections with combined postoperative radiation therapy have frequently been substituted for the more preferred segmental resections and resultant deformities. Presented are 15 cases of oral cavity cancer involving resection of the mandible, immediate radiation to 10,000 rad, and primary reconstruction as irradiated mandibular autografts. The longest following is 4 years and 3 months, with a success rate of 66%. Morbidity is minimal as compared to autogenous bone grafting. Tumor size, previous radiation, or use of regional flaps have not been a factor in the success of this method in reconstruction of the mandible primarily.
与下颌骨切除相关的美容和功能残疾一直是口腔癌直接侵犯下颌骨患者面临的主要问题。边缘性切除联合术后放疗常常替代了更理想的节段性切除以及由此产生的畸形。本文介绍了15例口腔癌患者，这些患者接受了下颌骨切除、即刻10000拉德放疗以及作为受照射下颌骨自体移植的一期重建。最长随访时间为4年3个月，成功率为66%。与自体骨移植相比，发病率极低。肿瘤大小、既往放疗或区域皮瓣的使用并非该方法在下颌骨一期重建成功中的影响因素。
