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鸡胚脊髓神经节中卫星细胞及其他非神经元细胞对成神经细胞变性的反应。

The response of the satellite and other non-neuronal cells to the degeneration of neuroblasts in chick embryo spinal ganglia.

作者信息

Pannese E

出版信息

Cell Tissue Res. 1978 Jun 26;190(1):1-14. doi: 10.1007/BF00210032.

DOI:10.1007/BF00210032
PMID:688330
Abstract

The responses of non-neuronal cells to the degeneration of neuroblasts were studied in the spinal ganglia of the chick embryo. Reactive changes of the non-neuronal cells were not apparent during the early stage of degeneration of the neuroblast, but during the later stages of degeneration evidence was found suggesting that non-neuronal cells subdivided and phagocytosed the affected neuroblasts. Three types of non-neuronal cells appeared to participate in the phagocytosis: satellite cells, cells resembling undifferentiated elements, and macrophages. The appearance of the latter coincided with the beginning of the vascularization of the ganglionic rudiment. The phagocytic capacity of satellite cells is discussed in the light of these and other studies by light and electron microscopy.

摘要

在鸡胚脊髓神经节中研究了非神经元细胞对神经母细胞退化的反应。在神经母细胞退化的早期阶段,非神经元细胞的反应性变化并不明显,但在退化的后期阶段,有证据表明非神经元细胞会细分并吞噬受影响的神经母细胞。三种类型的非神经元细胞似乎参与了吞噬作用:卫星细胞、类似于未分化成分的细胞和巨噬细胞。后者的出现与神经节原基血管化的开始相吻合。结合这些以及其他光镜和电镜研究,讨论了卫星细胞的吞噬能力。

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