Krupp P P, Frink R
Cell Tissue Res. 1978 Jun 26;190(1):181-5. doi: 10.1007/BF00210047.
Ultimobranchial cysts in the thyroid glands of rats receiving a diet adequate in vitamin A are lined with stratified squamous epithelium and contain non-keratinized cellular debris. The epithelium of these cysts in vitamin A deficient animals is keratinized, and their lumina contain keratinized cellular strands surrounding a core of cellular debris. Upon return to a diet adequate in vitamin A the epithelium returns to a non-keratinized state, and the lumina contain keratinized strands surrounded by cell fragments and desquamated whole cells. Occasionally these cysts have an epithelium that is highly irregular in appearance. The relationship of alterations in this tissue to possible subsequent development of neoplasias is discussed.
在摄入维生素A充足的饮食的大鼠甲状腺中的鳃后囊肿内衬复层鳞状上皮，并且含有非角化的细胞碎片。在维生素A缺乏的动物中，这些囊肿的上皮发生角化，并且它们的管腔含有围绕细胞碎片核心的角化细胞条索。当恢复到维生素A充足的饮食时，上皮恢复到非角化状态，并且管腔含有被细胞碎片和脱落的完整细胞包围的角化条索。偶尔，这些囊肿具有外观高度不规则的上皮。讨论了该组织的改变与肿瘤可能的后续发展之间的关系。
