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The binding of ketamine to plasma proteins: emphasis on human plasma.

作者信息

Dayton P G, Stiller R L, Cook D R, Perel J M

出版信息

Eur J Clin Pharmacol. 1983;24(6):825-31. doi: 10.1007/BF00607095.

DOI:10.1007/BF00607095
PMID:6884418
Abstract
摘要

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The binding of ketamine to plasma proteins: emphasis on human plasma.氯胺酮与血浆蛋白的结合：重点关注人血浆。
Eur J Clin Pharmacol. 1983;24(6):825-31. doi: 10.1007/BF00607095.
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Enantioselective plasma protein binding of bimoclomol.比莫克隆的对映体选择性血浆蛋白结合
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Effects of ketamine and propofol on muscarinic plateau potentials in rat neocortical pyramidal cells.氯胺酮和丙泊酚对大鼠新皮质锥体细胞毒蕈碱型平台电位的影响。

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Binding of psychotropic drugs to isolated alpha-acid glycoprotein.精神药物与分离的α-酸性糖蛋白的结合。
Biochem Pharmacol. 1981 Sep 1;30(17):2435-41. doi: 10.1016/0006-2952(81)90338-5.
2
The fate of thiopental in man and a method for its estimation in biological material.硫喷妥在人体中的代谢情况及其在生物材料中的测定方法。
J Pharmacol Exp Ther. 1950 Jan;98(1):85-96.
3
The distribution and excretion of phenobarbital.苯巴比妥的分布与排泄。
PLoS One. 2025 Jan 2;20(1):e0316262. doi: 10.1371/journal.pone.0316262. eCollection 2025.
4
In Vitro Hepatotoxicity of Routinely Used Opioids and Sedative Drugs.常用阿片类药物和镇静药物的体外肝毒性
Curr Issues Mol Biol. 2024 Mar 30;46(4):3022-3038. doi: 10.3390/cimb46040189.
5
Ketamine in Chronic Pain: A Review.氯胺酮治疗慢性疼痛：综述
Cureus. 2024 Feb 1;16(2):e53365. doi: 10.7759/cureus.53365. eCollection 2024 Feb.
6
Arylcyclohexylamine Derivatives: Pharmacokinetic, Pharmacodynamic, Clinical and Forensic Aspects.芳基环己基胺衍生物：药代动力学、药效学、临床和法医学方面。
Int J Mol Sci. 2022 Dec 8;23(24):15574. doi: 10.3390/ijms232415574.
7
Albumin alleviated esketamine-induced neuronal apoptosis of rat retina through downregulation of Zn-dependent matrix metalloproteinase 9 during the early development.白蛋白通过下调锌依赖性基质金属蛋白酶 9 减轻早期发育过程中氯胺酮诱导的大鼠视网膜神经细胞凋亡。
BMC Neurosci. 2022 Nov 16;23(1):66. doi: 10.1186/s12868-022-00753-5.
8
Expanding Role of NMDA Receptor Antagonists in the Management of Pain.NMDA 受体拮抗剂在疼痛管理中的作用不断扩大。
CNS Drugs. 2019 Apr;33(4):347-374. doi: 10.1007/s40263-019-00618-2.
9
Metabolism and metabolomics of ketamine: a toxicological approach.氯胺酮的代谢与代谢组学：一种毒理学方法。
Forensic Sci Res. 2017 Feb 20;2(1):2-10. doi: 10.1080/20961790.2017.1285219. eCollection 2017.
10
Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms.氯胺酮及其代谢产物的药理学：治疗机制的新视角。
Pharmacol Rev. 2018 Jul;70(3):621-660. doi: 10.1124/pr.117.015198.
J Clin Invest. 1957 Aug;36(8):1217-26. doi: 10.1172/JCI103518.
4
Changes in plasma drug binding and alpha 1-acid glycoprotein in mother and newborn infant.母亲和新生儿血浆药物结合及α1-酸性糖蛋白的变化。
Clin Pharmacol Ther. 1981 Apr;29(4):522-6. doi: 10.1038/clpt.1981.73.
5
Meperidine binding in maternal and fetal plasma.哌替啶在母体和胎儿血浆中的结合情况。
Clin Pharmacol Ther. 1981 Apr;29(4):472-9. doi: 10.1038/clpt.1981.65.
6
Pharmacokinetics and analgesic effect of ketamine in man.氯胺酮在人体中的药代动力学及镇痛作用
Br J Anaesth. 1981 Jan;53(1):27-30. doi: 10.1093/bja/53.1.27.
7
Pharmacokinetics of ketamine and two metabolites in the dog.氯胺酮及其两种代谢物在犬体内的药代动力学。
J Pharmacokinet Biopharm. 1980 Apr;8(2):193-202. doi: 10.1007/BF01065193.
8
Binding and displacement of basic, acidic and neutral drugs in normal and orosomucoid-deficient plasma.正常血浆和缺乏类粘蛋白血浆中碱性、酸性及中性药物的结合与置换
Clin Pharmacokinet. 1981 Sep-Oct;6(5):367-74. doi: 10.2165/00003088-198106050-00003.
9
Studies on the biotransformation of ketamine. 1-Identification of metabolites produced in vitro from rat liver microsomal preparations.氯胺酮的生物转化研究。1-大鼠肝脏微粒体制剂体外产生的代谢产物的鉴定。
Biomed Mass Spectrom. 1981 Nov;8(11):527-38. doi: 10.1002/bms.1200081103.
10
Contamination of albumin by alpha 1-acid glycoprotein.白蛋白被α1-酸性糖蛋白污染。
Biochem Pharmacol. 1981 Sep 15;30(18):2633-6. doi: 10.1016/0006-2952(81)90596-7.