Pönkä A, Sarna S
Eur J Respir Dis. 1983 Jul;64(5):360-8.
The hospital records of 150 patients with viral, mycoplasma and bacteraemic pneumococcal pneumonia were analyzed retrospectively to ascertain the discriminative value, regarding the aetiological diagnosis, of the information obtained on admission from the patient history, physical examination, simple laboratory tests and chest X-ray. With stepwise multiple discriminant analysis, the five best variables led to correct classification of 92% of bacteraemic pneumococcal, 88% of mycoplasmal, 76% of viral, and 85% of all pneumonias. Addition of a further nine variables increased the total discriminating capacity to only 89%. The best discriminating variables were the C-reactive protein determination, the presence or absence of predisposing disease or previous antibiotic treatment, the erythrocyte sedimentation rate, the presence of lymphocytosis and the band neutrophile count.
回顾性分析了150例病毒性、支原体性和菌血症性肺炎患者的医院记录,以确定从患者病史、体格检查、简单实验室检查和胸部X线检查中获得的信息对于病因诊断的鉴别价值。通过逐步多元判别分析,五个最佳变量可使92%的菌血症性肺炎、88%的支原体性肺炎、76%的病毒性肺炎以及85%的所有肺炎得到正确分类。再增加九个变量后,总鉴别能力仅提高到89%。最佳鉴别变量为C反应蛋白测定、是否存在易感疾病或先前的抗生素治疗、红细胞沉降率、淋巴细胞增多的存在以及杆状中性粒细胞计数。