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泛硫乙胺对豚鼠离体心肌的正性肌力和负性变时作用。

Positive inotropic and negative chronotropic effect of pantethine on isolated cardiac muscle of guinea-pigs.

作者信息

Minami M, Yasuda H, Saito H

出版信息

Experientia. 1983 Sep 15;39(9):1028-30. doi: 10.1007/BF01989786.

DOI:10.1007/BF01989786
PMID:6884490
Abstract

It was demonstrated that pantethine, a component of co-enzyme A, produces positive inotropic and negative chronotropic actions in isolated cardiac muscle preparations from guinea-pigs.

摘要

已证实，泛酰硫乙胺作为辅酶A的一种成分，在豚鼠离体心肌制备物中可产生正性肌力作用和负性变时作用。

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本文引用的文献

1
Determination and properties of an unidentified growth factor required by Lactobacillus bulgaricus.保加利亚乳杆菌所需一种未知生长因子的测定及特性
J Biol Chem. 1949 Feb;177(2):933-40.
2
The synthesis of coenzyme A from panthetheine: preparation and properties of panthetheine kinase.由泛酰巯基乙胺合成辅酶A：泛酰巯基乙胺激酶的制备及性质
J Biol Chem. 1954 Apr;207(2):761-5.
3
Potentiation of toxicity and positive inotropic effect of ouabain by furosemide in guinea pig heart.
J Toxicol Sci. 1982 Feb;7(1):27-34. doi: 10.2131/jts.7.27.
4
Effect of pantethine on myocardial pH reduced by partial occlusion of the coronary artery in dogs with special reference to the myocardial levels of adenosine triphosphate, creatine phosphate, and lactate.泛硫乙胺对冠状动脉部分闭塞所致犬心肌pH降低的影响，特别涉及三磷酸腺苷、磷酸肌酸和乳酸的心肌水平。
Arch Int Pharmacodyn Ther. 1982 Feb;255(2):281-92.
5
[Biological studies of pantethine. 10. Effects of anesthetics on gastrointestinal-motility promoting effect of pantethine].
Nihon Yakurigaku Zasshi. 1972 May;68(3):255-64.