Bleker O P, Ketting B W, van Wayjen-Eecen B, Kloosterman G J
Gynecol Oncol. 1983 Aug;16(1):56-62. doi: 10.1016/0090-8258(83)90009-4.
From 1961 through 1980, 388 patients with cervical carcinoma stage IB (272) and stage IIA (116) were treated by radical hysterectomy and pelvic lymphadenectomy. The operation specimens were divided into four groups: no involvement of the parametrium and pelvic lymph nodes (71.4%), involvement of the parametrium alone (7.2%), involvement of the pelvic lymph nodes alone (11.9%), and involvement of both the parametrium and pelvic lymph nodes (9.5%). Two hundred thirty-eight patients were followed for at least 5 years. The corrected 5-year survival figures for these four groups (stages IB and IIA together) were 90.3, 75.0, 62.1, and 50.0%, respectively. The differences are of statistical significance (P less than 0.005). Not only the stage of disease and involvement of the lymph nodes, but clearly also the involvement of the parametrium is of significance for the results of treatment in cervical cancer.
1961年至1980年期间，388例IB期（272例）和IIA期（116例）宫颈癌患者接受了根治性子宫切除术和盆腔淋巴结清扫术。手术标本分为四组：宫旁组织和盆腔淋巴结均未受累（71.4%）、仅宫旁组织受累（7.2%）、仅盆腔淋巴结受累（11.9%）、宫旁组织和盆腔淋巴结均受累（9.5%）。238例患者至少随访了5年。这四组（IB期和IIA期合并）的校正5年生存率分别为90.3%、75.0%、62.1%和50.0%。差异具有统计学意义（P<0.005）。不仅疾病分期和淋巴结受累情况，而且宫旁组织受累情况显然对宫颈癌的治疗结果也具有重要意义。
