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肠上皮型黏液性卵巢囊腺瘤的恶性转化

Malignant transformation of mucinous ovarian cystadenomas of intestinal epithelial type.

作者信息

Szymańska K, Szamborski J, Miechowiecka N, Czerwiński W

出版信息

Histopathology. 1983 Jul;7(4):497-509. doi: 10.1111/j.1365-2559.1983.tb02263.x.

DOI:10.1111/j.1365-2559.1983.tb02263.x
PMID:6884997
Abstract

We studied 116 benign and 18 borderline malignant mucinous ovarian cystadenomas. Their epithelial lining was compared with normal epithelium of the uterine cervix and that of the small and large intestines, by both light and electron microscopy as well as histochemically. This morphological and histochemical analysis enabled us to subdivide mucinous cystadenomas into cervical, mixed and intestinal epithelial types. The epithelial cells of intestinal type tumours exhibited histochemical reactions very similar to, or identical with, those found in both immature and mature cells of intestinal mucosa. Malignant transformation was found in intestinal type mucinous cystadenomas only. Ultrastructural investigations of six neoplasms (four of intestinal and two of cervical epithelium type) confirmed the results found with the light microscope.

摘要

我们研究了116例良性和18例交界性恶性黏液性卵巢囊腺瘤。通过光学显微镜、电子显微镜以及组织化学方法,将其上皮内衬与子宫颈正常上皮以及小肠和大肠的正常上皮进行了比较。这种形态学和组织化学分析使我们能够将黏液性囊腺瘤细分为宫颈型、混合型和肠上皮型。肠型肿瘤的上皮细胞表现出的组织化学反应与肠黏膜未成熟和成熟细胞中发现的反应非常相似或相同。仅在肠型黏液性囊腺瘤中发现了恶性转化。对6个肿瘤(4个肠上皮型和2个宫颈上皮型)的超微结构研究证实了光学显微镜下的结果。

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1
Malignant transformation of mucinous ovarian cystadenomas of intestinal epithelial type.肠上皮型黏液性卵巢囊腺瘤的恶性转化
Histopathology. 1983 Jul;7(4):497-509. doi: 10.1111/j.1365-2559.1983.tb02263.x.
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Mucinous tumors of the ovary. Ultrastructural studies of mucinous cystadenomas with histogenetic considerations.卵巢黏液性肿瘤。黏液性囊腺瘤的超微结构研究及组织发生学思考
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Expression of a homeobox gene (SIX5) in borderline ovarian tumours.同源框基因(SIX5)在卵巢交界性肿瘤中的表达
J Clin Pathol. 2000 Mar;53(3):212-7. doi: 10.1136/jcp.53.3.212.
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Intestinal differentiation in ovarian mucinous tumours.
Virchows Arch A Pathol Anat Histopathol. 1990;417(3):197-201. doi: 10.1007/BF01600134.