Retrograde growth of myelinated fibres in experimental neuromas.

Retrograde growth of myelinated fibre sprouts following section of mouse sural nerves has been investigated. The results indicate that many sprouts grow relatively long distances proximally along the nerve trunk. The largest number of such sprouts was observed at 10 weeks after nerve section, with a decrease by 9 months. It has been shown that the retrogradely growing sprouts arise within the neuroma and not more proximally on the nerve.