Barbalias G A, Meares E M, Sant G R
J Urol. 1983 Sep;130(3):514-7. doi: 10.1016/s0022-5347(17)51281-1.
Twenty patients with prostatodynia were studied urodynamically with synchronous video-pressure-flow studies and electromyography of the external urethral sphincter. The most striking finding was a significant increase in maximum urethral closure pressure compared to an age and sex-matched control group. Typically, peak and average urinary flow rates were decreased. Another prominent feature was incomplete funneling of the bladder neck during voiding with an accompanying urethral narrowing at the level of the external urethral sphincter. These findings are not consistent with a diagnosis of tension myalgia of the pelvic floor or detrusor-striated sphincter dyssynergia but suggest a primary abnormality involving the pelvic sympathetic nervous system. We believe that more advanced methods than those available currently are needed to elucidate fully the role of the autonomic nervous system, especially its sympathetic component, in the etiology of prostatodynia.
对20例前列腺痛患者进行了尿动力学研究，同步进行了视频压力流研究和尿道外括约肌肌电图检查。最显著的发现是，与年龄和性别匹配的对照组相比，最大尿道闭合压显著升高。通常，尿流率峰值和平均尿流率降低。另一个突出特征是排尿时膀胱颈漏斗形成不完全，并伴有尿道外括约肌水平的尿道狭窄。这些发现与盆底紧张性肌痛或逼尿肌-横纹肌括约肌协同失调的诊断不一致，但提示存在涉及盆腔交感神经系统的原发性异常。我们认为，需要比目前可用的方法更先进的方法，以充分阐明自主神经系统，尤其是其交感神经成分在前列腺痛病因中的作用。
