Tomera K M, Farrow G M, Lieber M M
J Urol. 1983 Oct;130(4):657-9. doi: 10.1016/s0022-5347(17)51388-9.
Sarcomatoid renal carcinoma made up 1 per cent of renal parenchymal tumors resected from 1967 to 1980. The majority of patients with this aggressive type of renal carcinoma were symptomatic and had a palpable renal mass at the time of diagnosis. Only 2 of 13 patients had tumor confined within the renal capsule at the time of operation. One of these patients survived and 12 of 13 died rapidly of metastatic renal carcinoma, with a median survival of 6.3 months from the time of diagnosis. This distinctive histologic variant of renal carcinoma has a highly malignant biological behavior and, as effective adjuvant treatment for renal carcinoma becomes available, should be one of the tumor types treated vigorously.
1967年至1980年期间，肉瘤样肾细胞癌占肾实质肿瘤切除病例的1%。大多数患这种侵袭性肾癌的患者有症状，诊断时可触及肾脏肿块。13例患者中只有2例在手术时肿瘤局限于肾包膜内。其中1例患者存活，13例中的12例因转移性肾癌迅速死亡，从诊断时起的中位生存期为6.3个月。这种独特的肾癌组织学变体具有高度恶性的生物学行为，随着有效的肾癌辅助治疗方法的出现，它应成为积极治疗的肿瘤类型之一。
