The oscillatory network of glycolysis: a model for multiple phase output derived from a single master oscillator.

In oscillatory glycolysing yeast cells the reaction rates of 11 enzymic steps are almost completely in phase whereas the concentrations of intermediates fluctuate with highly different phases. Metabolite concentrations depend on the amplitudes of reaction rates even more than on their phases. In this way almost, synchronized enzymes can given rise to a variety of phases, resembling a "master oscillatory" which controls a series of peripheric event with different phases.