Leong A S, Gove D W
Pathology. 1983 Apr;15(2):189-92. doi: 10.3109/00313028309084711.
Silicone pump head tubings were subjected to mechanical stress under conditions which simulated hemodialysis. Examination by scanning electron microscopy revealed evidence of abrasion on the internal surface of the tubing following 5 h of normal use. Damage was extensive after 20 h and large splits and lacerations were present on the internal surface after 96 h of pumping. Atomic absorption spectrometric analysis of the circulated blood provided confirmatory evidence of spallation, and concentrations of polydimethylsiloxane (silicone) rose in parallel with the duration of use. While spallation has previously been demonstrated from polyvinyl chloride, latex and silicone tubings during the faster flow rates of cardiopulmonary bypass, this report is the first to show silicone spallation at flow rates obtained during hemodialysis.
硅树脂泵头管道在模拟血液透析的条件下承受机械应力。通过扫描电子显微镜检查发现，正常使用5小时后，管道内表面有磨损迹象。20小时后损伤严重，泵送96小时后内表面出现大的裂缝和撕裂。对循环血液进行原子吸收光谱分析提供了剥落的确证，聚二甲基硅氧烷（硅树脂）的浓度随着使用时间的延长而升高。虽然先前已证实在体外循环更快流速期间聚氯乙烯、乳胶和硅树脂管道会发生剥落，但本报告首次表明在血液透析期间所获得的流速下硅树脂会发生剥落。
