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儿童群体血压筛查的有效性

Validity of mass blood pressure screening in children.

作者信息

Fixler D E, Laird W P

出版信息

Pediatrics. 1983 Oct;72(4):459-63.

PMID:6889060
Abstract

The validity of a mass blood pressure screening program carried out on Dallas high school students who were followed for at least 3 years is reported. Blood pressure results on initial screening in the tenth grade were related to outcome blood pressure status. The frequency of initial blood pressure elevation (systolic and/or diastolic pressure above the 95th percentile) was 10%, whereas the prevalence of sustained elevation in the tenth grade was less than 2%. The initial screening correctly identified 72% of those who had sustained elevations on all three tenth grade examinations (sensitivity), and correctly identified 91% of those who did not have sustained elevations (specificity). However, the predictive value of an initial positive screening result was low, at only 17% (152/900). The high proportion of false-positive results represents a significant cost to any blood pressure screening program, both in economic terms and in its potential for creating anxiety among families with children having only transiently elevated blood pressure. Because the costs are high and the yield from mass screening of children low, case finding of childhood hypertension should remain the responsibility of the physician who sees children in the clinical setting.

摘要

本文报告了一项针对达拉斯高中生开展的大规模血压筛查项目的有效性,这些学生至少接受了3年的随访。十年级初次筛查时的血压结果与最终血压状况相关。初次血压升高(收缩压和/或舒张压高于第95百分位数)的频率为10%,而十年级持续性血压升高的患病率低于2%。初次筛查正确识别了在十年级的三次检查中均出现持续性血压升高者中的72%(敏感性),并正确识别了未出现持续性血压升高者中的91%(特异性)。然而,初次筛查阳性结果的预测价值较低,仅为17%(152/900)。假阳性结果的高比例对任何血压筛查项目来说都是一项重大成本,无论是在经济方面,还是在可能给仅有短暂血压升高儿童的家庭带来焦虑方面。由于成本高昂且儿童大规模筛查的收益较低,儿童高血压的病例发现仍应由在临床环境中诊治儿童的医生负责。

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