Ahmad T, Ahmad I
Pol J Pharmacol Pharm. 1983;35(1):69-75.
Aqueous sulfacetamide and sulfanilamide solutions were photolyzed at pH 1-13 and in the presence of various antioxidants and a chelating agent (pH 7.0). The rate constants for the photodegradation of sulfacetamide and sulfanilamide were determined. Sodium metabisulfite and thiourea were the best antioxidants for the photostabilization of sulfacetamide and sulfanilamide solutions respectively. Sodium edetate is also an effective stabilizer in sulfacetamide solutions. The efficiency of the antioxidants on the basis of product distribution and the kinetic results is discussed.
在pH值为1 - 13的条件下，以及在各种抗氧化剂和一种螯合剂（pH 7.0）存在的情况下，对水相中的磺胺醋酰和磺胺进行了光解。测定了磺胺醋酰和磺胺光降解的速率常数。焦亚硫酸钠和硫脲分别是使磺胺醋酰和磺胺溶液光稳定的最佳抗氧化剂。乙二胺四乙酸钠在磺胺醋酰溶液中也是一种有效的稳定剂。基于产物分布和动力学结果，讨论了抗氧化剂的效率。
