Berman Doreen, Rodin Barbara E
Department of Psychology, Queens College, Flushing, N.Y. 11367 U.S.A.
Pain. 1982 Jul;13(3):307-311. doi: 10.1016/0304-3959(82)90020-3.
Forty-four rats were subjected to unilateral intradural section of dorsal roots T13-L6. Of these, 10 were housed alone and 34 were housed with female rats. Each of the 10 animals housed alone-self-mutilated to an extreme degree, with 7 cannibalizing the denervated limb. Only of the animals housed with a female showed any sign of self-biting, and this was a minor, isolated incident. These results are discussed with particular reference to dorsal rhizotomy in rats serving as a model of chronic pain.
44只大鼠接受了T13 - L6背根的单侧硬膜内切断术。其中,10只单独饲养,34只与雌性大鼠一起饲养。单独饲养的10只动物中,每只都出现了极其严重的自残行为,有7只吃掉了去神经支配的肢体。只有与雌性大鼠一起饲养的动物表现出任何自咬迹象,且这只是一个轻微的、孤立的事件。本文结合大鼠背根切断术作为慢性疼痛模型这一情况对这些结果进行了讨论。