“处理方式”与丙烯酰胺对大鼠内分泌反应的相互作用。
Interactions between "handling" and acrylamide on endocrine responses in rats.
作者信息
Uphouse L L, Nemeroff C B, Mason G, Prange A J, Bondy S C
出版信息
Neurotoxicology. 1982 Jul;3(1):121-5.
PMID:6890183
Abstract
Serum prolactin and corticosterone levels were measured in rats that had been gentled by handling and that had been exposed to 100 mg/kg acrylamide. Handling reduced both corticosterone and prolactin levels. Acrylamide had no effect on corticosterone levels. Prolactin levels were significantly lower in acrylamide-exposed nonhandled animals. These findings are discussed in terms of their implications for studying the effects of toxicants on neural function.
摘要
对经处理温顺的大鼠以及暴露于100毫克/千克丙烯酰胺的大鼠测量了血清催乳素和皮质酮水平。处理降低了皮质酮和催乳素水平。丙烯酰胺对皮质酮水平没有影响。在暴露于丙烯酰胺的未处理动物中，催乳素水平显著较低。根据这些发现对研究毒物对神经功能的影响的意义进行了讨论。
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