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Structures of the adducts formed between [Pt(dien)Cl]Cl and DNA in vitro.
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The new antitumor compound, cis-[Pt(NH3)2(4-methylpyridine)Cl]Cl, does not form N7,N7-d(GpG) chelates with DNA. An unexpected preference for platinum binding at the 5'G in d(GpG).
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Pt(II) complexes of unsubstituted guanine and 7-methylguanine.
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Temporal behavior of DNA thermal stability in the presence of platinum compounds. Role of monofunctional and bifunctional adducts.
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DNA-platinum interactions in vitro with trans- and cis-Pt(NH3)2Cl2.
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Interaction of platinum compounds with short oligodeoxynucleotides containing guanine and cytosine.
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A circular dichroism study of DNA.platinum complexes. Differentiation between monofunctional, cis-bidentate and trans-bidentate platinum fixation on a series of DNAs.
Eur J Biochem. 1978 Feb;83(2):375-85. doi: 10.1111/j.1432-1033.1978.tb12103.x.
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Thiolate bridging and metal exchange in adducts of a zinc finger model and Pt(II) complexes: biomimetic studies of protein/Pt/DNA interactions.
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Adducts of the antitumor drug cis-diamminedichloroplatinum(II) with DNA: formation, identification, and quantitation.
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Alterations in the d(CpGpT) structure in solution as a result of [PtCl(diethylenetriamine)]+ binding.
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Polymerase bypass of N7-guanine monoadducts of cisplatin, diepoxybutane, and epichlorohydrin.
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Production of platinum atom nanoclusters at one end of helical plant viruses.
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Mechanistic studies of the modulation of cleavage activity of topoisomerase I by DNA adducts of mono- and bi-functional PtII complexes.
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Reaction of cis-diamminedichloroplatinum (II) and DNA in B or Z conformation.
EMBO J. 1984 Jun;3(6):1273-9. doi: 10.1002/j.1460-2075.1984.tb01962.x.
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The primary mode of binding of cisplatin to a B-DNA dodecamer: C-G-C-G-A-A-T-T-C-G-C-G.
EMBO J. 1984 May;3(5):1201-6. doi: 10.1002/j.1460-2075.1984.tb01951.x.
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Repair of cis-platinum-DNA adducts by ABC excinuclease in vivo and in vitro.
J Bacteriol. 1985 Sep;163(3):817-23. doi: 10.1128/jb.163.3.817-823.1985.
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Treatment of DNA with ammonium bicarbonate or thiourea can lead to underestimation of platinum-DNA monoadducts.
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FURTHER STUDIES ON THE ALKYLATION OF NUCLEIC ACIDS AND THEIR CONSTITUENT NUCLEOTIDES.
Biochem J. 1963 Oct;89(1):127-38. doi: 10.1042/bj0890127.
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Viscosity, nicking, thermal and alkaline denaturation studies on three classes of DNA-platinum complex.
Biochim Biophys Acta. 1981 May 29;653(3):305-15. doi: 10.1016/0005-2787(81)90187-8.
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Induction of recA protein in Escherichia coli by three platinum (II) compounds.
Biochem Biophys Res Commun. 1982 Mar 15;105(1):202-8. doi: 10.1016/s0006-291x(82)80031-4.
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Preliminary characterization of the adducts formed between the antitumor compounds cis-Pt(NH3)2Cl2 and DNA.
Biochem Biophys Res Commun. 1982 Feb 26;104(4):1394-400. doi: 10.1016/0006-291x(82)91404-8.
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Post replication repair in an excision defective strain of Escherichia coli following treatment with cis dichlorodiammineplatinum(II).
Biochem Biophys Res Commun. 1982 Jan 29;104(2):693-700. doi: 10.1016/0006-291x(82)90692-1.
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Mutagenicity, tumorigenicity, and electrophilic reactivity of the stereoisomeric platinum(II) complexes of 1,2-diaminocyclohexane.
Cancer Res. 1981 Nov;41(11 Pt 1):4368-77.
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Binding of the anticancer drug cis-dichlorodiammineplatinum to 3'(2')-guanosine monophosphate and nucleic acids.
Anticancer Res. 1981;1(6):383-8.
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Use of exonuclease III to determine the site of stable lesions in defined sequences of DNA: the cyclobutane pyrimidine dimer and cis and trans dichlorodiammine platinum II examples.
Nucleic Acids Res. 1981 Sep 25;9(18):4595-609. doi: 10.1093/nar/9.18.4595.
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Kinetics and mechanism of the acid-catalyzed hydrolysis of some purine nucleosides.
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The properties of 7-methylguanine-containing templates for ribonucleic acid polymerase.
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