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人声带小血管的超微结构研究

Ultrastructural study on the small blood vessels of human vocal cords.

作者信息

Frenzel H, Kleinsasser O

出版信息

Arch Otorhinolaryngol. 1982;236(2):147-60. doi: 10.1007/BF00454035.

DOI:10.1007/BF00454035
PMID:6890800
Abstract

Small blood vessels of human vocal cords were examined by electron microscopy. The endothelial cells contain a large number of filaments. Two kinds of filaments could be differentiated: Short intermediate filaments with a diameter of 10-12 nm, which were localized in the pericaryon, and bundles of thin filaments with a periodicity of 480 nm lying beneath the luminal cellular membrane. The basement membrane of capillaries, arteries, and veins was lamellate. Between the outermost, not fully closed lamellae, myocytes or pericytes could be seen. Both the lamellate basement membranes and the large number of intermediate filaments in the endothelial cells are discussed as stabilizing structures in blood vessels which are exposed to high mechanical forces. The bundles of cross-striated thin filaments may possibly increase the permeability of the vessel wall by their contraction, permitting the well-known fast development of edema in the vocal cords. The importance of Weibel-Palade bodies, which could be disclosed in the endothelial cells in large numbers, is not yet known.

摘要

采用电子显微镜对人声带的小血管进行了检查。内皮细胞含有大量细丝。可区分出两种细丝:直径为10 - 12纳米的短中间丝,位于核周;以及位于管腔细胞膜下方、具有480纳米周期性的细束丝。毛细血管、动脉和静脉的基底膜呈层状。在最外层未完全封闭的板层之间,可以看到肌细胞或周细胞。层状基底膜和内皮细胞中大量的中间丝被认为是血管中承受高机械力的稳定结构。横纹细束丝可能通过收缩增加血管壁的通透性,从而导致声带中众所周知的快速水肿形成。在内皮细胞中大量发现的魏尔-帕拉德小体的重要性尚不清楚。

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本文引用的文献

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Studies on inflammation. 1. The effect of histamine and serotonin on vascular permeability: an electron microscopic study.炎症研究。1. 组胺和血清素对血管通透性的影响:一项电子显微镜研究。
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