Clemm C, Hartenstein R, Wilmanns W
Fortschr Med. 1982 Oct 21;100(39):1783-8.
Cis-(diammine-dichloro-) platinum containing polychemotherapy combined with surgery has markedly improved the prognosis of cancer of the testis even in the metastatic stage. Important is a quickly obtained diagnosis. The histological staging can be rendered more precise by means of immunoperoxidase technique, the clinical staging with the help of tumor markers (alpha FP, beta hCG). Polychemotherapy is indicated in the case of seminoma in stage IV or with elevated beta hCG, teratoma in stage IIB-IV, chorion carcinoma in every stage, and should only be carried out in specialized oncological centers. Delayed and inconsequent treatment must be avoided. Only then more than 75% of patients treated with polychemotherapy can be freed from tumor, even up to 50% of those cases with unfavorable histology and extensive tumor stage.
含顺式（二胺二氯）铂的联合化疗与手术相结合，即使在转移性阶段，也显著改善了睾丸癌的预后。快速获得诊断很重要。通过免疫过氧化物酶技术可使组织学分期更精确，借助肿瘤标志物（甲胎蛋白、β-人绒毛膜促性腺激素）可进行临床分期。对于IV期精原细胞瘤或β-人绒毛膜促性腺激素升高的情况、IIB-IV期畸胎瘤、各期绒毛膜癌，均需进行联合化疗，且应仅在专业肿瘤中心开展。必须避免治疗延迟和不连贯。只有这样，超过75%接受联合化疗的患者才能摆脱肿瘤，即使是组织学不良和肿瘤分期广泛的病例，这一比例也可达50%。
