人类白细胞抗原（HLA）抗原与尿布银屑病样皮炎

HLA-antigens and psoriasiform napkin dermatitis.

作者信息

Skoven I G, Hjortshøj A

出版信息

Dermatologica. 1978;157(4):225-8. doi: 10.1159/000250837.

Abstract

HLA typing was performed in 14 patients with psoriasiform napkin dermatitis (PND). Only 2 patients carried one of the three antigens (HLA-B13, B17, Bw37) associated with psoriasis vulgaris. The frequency of these antigens in PND corresponds to that in healthy controls, but differs significantly (p less than 0.01) from that in a population of psoriatics. Our results indicate that patients with PND are not true psoriatics, and that PND and psoriasis are different etiological entities.

摘要

对14例尿布银屑病样皮炎（PND）患者进行了HLA分型。仅2例患者携带与寻常型银屑病相关的三种抗原（HLA - B13、B17、Bw37）之一。这些抗原在PND中的频率与健康对照者中的频率相当，但与银屑病患者群体中的频率有显著差异（p小于0.01）。我们的结果表明，PND患者并非真正的银屑病患者，并且PND和银屑病是不同的病因实体。