Porta S, Egger G, Sattelberger R, Sadjak A, Supanz S
Exp Pathol. 1981;19(3):172-8. doi: 10.1016/s0232-1513(81)80061-8.
Adrenal depletion in rats due to hypoglycemia was effected by prolonged administration of adrenaline, without artificial increase in insulin levels. In spite of significantly enhanced catecholamine turnover in this stadium Golgi complexes - which are usually reported to develop hypertrophy during adrenal depletion using insulin induced hypoglycaemia - could never be observed. This leads to the conclusions, that firstly the presence of hypertrophic Golgi complexes is not necessarily linked with increased catecholamine turnover and secondly that permanent adrenalin application suppresses and insulin application promotes the formation of Golgi systems. Moreover, our electromicrographs do strongly suggest, that catecholamine turnover is linked with the rough endoplasmatic reticulum.
在不人为提高胰岛素水平的情况下，通过长时间给予肾上腺素，可导致大鼠因低血糖而出现肾上腺耗竭。尽管在此阶段儿茶酚胺周转率显著提高，但从未观察到高尔基体复合体——通常报道在使用胰岛素诱导低血糖导致肾上腺耗竭时会发生肥大。由此得出结论，首先，肥大的高尔基体复合体的存在不一定与儿茶酚胺周转率增加有关；其次，持续应用肾上腺素会抑制，而应用胰岛素会促进高尔基体系统的形成。此外，我们的电子显微镜照片有力地表明，儿茶酚胺周转率与粗面内质网有关。
