Tabidze L V, Kagan V E, Shukoliukov S A, Ivanov I I
Biofizika. 1980 Mar-Apr;25(2):340-1.
To elucidate the mechanisms of stabilization of biomembranes by tocopherols, the effect of alpha-tocopherol on thermal stability of rhodopsin in photoreceptor membranes of walleye pollock was studied. It was shown that alpha-tocopherol changed the rate constants of rhodopsin thermal denaturation neither in native, nor in peroxidised or treated with phospholipase A2 rod outer segments. Substitution of phospholipid microenvironment of rhodopsin in photoreceptor membrane by alpha-tocopherol did not result in stabilization of the visual pigment too.
为阐明生育酚对生物膜的稳定机制,研究了α-生育酚对狭鳕鱼光感受器膜中视紫红质热稳定性的影响。结果表明,α-生育酚在天然、过氧化或用磷脂酶A2处理的视杆外段中均未改变视紫红质热变性的速率常数。用α-生育酚替代光感受器膜中视紫红质的磷脂微环境也不会导致视觉色素的稳定。