[1-β-巯基-β,β-环戊亚甲基丙酸],2-(O-甲基)酪氨酸]精氨酸加压素和[1-β-巯基-β,β-环戊亚甲基丙酸]精氨酸加压素，两种对精氨酸加压素的升压反应具有高度强效的拮抗剂。 - Suppr

Suppr

超能文献

[1-beta-Mercapto-beta,beta-cyclopentamethylenepropionic acid),2-(O-methyl)tyrosine ]argine-vasopressin and [1-beta-mercapto-beta,beta-cyclopentamethylenepropionic acid)]argine-vasopressine, two highly potent antagonists of the vasopressor response to arginine-vasopressin.

作者信息

Kruszynski M, Lammek B, Manning M, Seto J, Haldar J, Sawyer W H

出版信息

J Med Chem. 1980 Apr;23(4):364-8. doi: 10.1021/jm00178a003.

DOI:10.1021/jm00178a003

PMID:6892930

Abstract

摘要

相似文献

[1-beta-Mercapto-beta,beta-cyclopentamethylenepropionic acid),2-(O-methyl)tyrosine ]argine-vasopressin and [1-beta-mercapto-beta,beta-cyclopentamethylenepropionic acid)]argine-vasopressine, two highly potent antagonists of the vasopressor response to arginine-vasopressin.[1-β-巯基-β,β-环戊亚甲基丙酸],2-(O-甲基)酪氨酸]精氨酸加压素和[1-β-巯基-β,β-环戊亚甲基丙酸]精氨酸加压素，两种对精氨酸加压素的升压反应具有高度强效的拮抗剂。

J Med Chem. 1980 Apr;23(4):364-8. doi: 10.1021/jm00178a003.

Synthesis and some pharmacological properties of 18 potent O-alkyltyrosine-substituted antagonists of the vasopressor responses to arginine-vasopressin.18种强效的O-烷基酪氨酸取代的精氨酸加压素血管升压反应拮抗剂的合成及某些药理特性

J Med Chem. 1985 Oct;28(10):1485-91. doi: 10.1021/jm00148a019.

Design of potent antagonists of the vasopressor response to arginine-vasopressin.精氨酸加压素升压反应强效拮抗剂的设计

J Med Chem. 1978 Sep;21(9):850-3. doi: 10.1021/jm00207a002.

N-Acetyl-[2-(O-methyl)tyrosine]arginine-vasopressin, an interesting antagonist of the vasopressor response to vasopressin.

J Med Chem. 1980 Jun;23(6):696-8. doi: 10.1021/jm00180a027.

Prolonged inhibition of pressor response to vasopressin by a potent specific antagonist, [1-(beta-mercapto-beta, beta-cyclopentamethylenepropionic acid) 2-(O-methyl)tyrosine]arginine-vasopressin.一种强效特异性拮抗剂[1-(β-巯基-β,β-环戊亚甲基丙酸)2-(O-甲基)酪氨酸]精氨酸加压素对加压素升压反应的长期抑制作用。

Can J Physiol Pharmacol. 1981 Sep;59(9):1008-12. doi: 10.1139/y81-153.

Synthesis of arginine-vasopressins, modified in positions 1 and 2, as antagonists of the vasopressor response to the parent hormone.在第1和第2位进行修饰的精氨酸加压素的合成，作为对母体激素的升压反应的拮抗剂。

J Med Chem. 1988 Mar;31(3):603-6. doi: 10.1021/jm00398a018.

Synthetic antagonists of in vivo antidiuretic and vasopressor responses to arginine-vasopressin.对精氨酸加压素体内抗利尿和升压反应的合成拮抗剂。

J Med Chem. 1981 Jun;24(6):701-6. doi: 10.1021/jm00138a012.

Design of potent and selective antagonists of the vasopressor responses to arginine-vasopressin.精氨酸加压素升压反应的强效和选择性拮抗剂的设计

J Med Chem. 1982 Apr;25(4):408-14. doi: 10.1021/jm00346a015.

Synthesis and some pharmacological properties of potent and selective antagonists of the vasopressor (V1-receptor) response to arginine-vasopressin.精氨酸加压素血管升压素（V1受体）反应的强效和选择性拮抗剂的合成及某些药理学特性

J Med Chem. 1992 Jan 24;35(2):382-8. doi: 10.1021/jm00080a027.

Synthesis of 8-D-arginine vasopressin analogues, modified in position 1 as antagonists of the vasopressor response to the parent hormone.8-D-精氨酸加压素类似物的合成，其在第1位进行了修饰，作为对母体激素升压反应的拮抗剂。

Pol J Pharmacol Pharm. 1988 Jul-Aug;40(4):423-8.

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