• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Conditions for the selective labelling of the 66 000 dalton chain of the acetylcholine receptor by the covalent non-competitive blocker 5-azido-[3H]trimethisoquin.

作者信息

Saitoh T, Oswald R, Wennogle L P, Changeux J P

出版信息

FEBS Lett. 1980 Jul 11;116(1):30-6. doi: 10.1016/0014-5793(80)80522-9.

DOI:10.1016/0014-5793(80)80522-9
PMID:6893305
Abstract
摘要

相似文献

1
Conditions for the selective labelling of the 66 000 dalton chain of the acetylcholine receptor by the covalent non-competitive blocker 5-azido-[3H]trimethisoquin.通过共价非竞争性阻断剂5-叠氮基-[³H]三甲异喹啉对乙酰胆碱受体66000道尔顿链进行选择性标记的条件。
FEBS Lett. 1980 Jul 11;116(1):30-6. doi: 10.1016/0014-5793(80)80522-9.
2
Selective labeling of the delta subunit of the acetylcholine receptor by a covalent local anesthetic.通过共价局部麻醉剂对乙酰胆碱受体δ亚基进行选择性标记。
Biochemistry. 1981 Dec 8;20(25):7166-74. doi: 10.1021/bi00528a018.
3
Selective labelling by [3H]trimethisoquin azide of polypeptide chains present in acetylcholine receptor-rich membranes from Torpedo marmorata.用[3H]三甲异喹嗪对来自电鳐富含乙酰胆碱受体的膜中存在的多肽链进行选择性标记。
FEBS Lett. 1980 Feb 25;111(1):29-34. doi: 10.1016/0014-5793(80)80754-x.
4
Dissection of the 66 000-dalton subunit of the acetylcholine receptor.乙酰胆碱受体66000道尔顿亚基的剖析
Biochemistry. 1981 Apr 28;20(9):2492-7. doi: 10.1021/bi00512a020.
5
Affinity labelling by bromoacetylcholine of a characteristic subunit in the acetylcholine receptor from muscle and Torpedo electric organ.用溴乙酰胆碱对来自肌肉和电鳐电器官的乙酰胆碱受体中的一个特征亚基进行亲和标记。
FEBS Lett. 1979 Dec 1;108(1):20-4. doi: 10.1016/0014-5793(79)81169-2.
6
Synthesis and pharmacological activity on Electrophorus electricus electroplaque of photoaffinity labelling derivatives of the non-competitive blockers di- and tri-methisoquin.
FEBS Lett. 1980 Feb 25;111(1):23-8. doi: 10.1016/0014-5793(80)80753-8.
7
Ultraviolet light-induced labeling by noncompetitive blockers of the acetylcholine receptor from Torpedo marmorata.用非竞争性阻滞剂对斑纹电鳐乙酰胆碱受体进行紫外线诱导标记。
Proc Natl Acad Sci U S A. 1981 Jun;78(6):3925-9. doi: 10.1073/pnas.78.6.3925.
8
Demonstration and affinity labeling of a stereoselective binding site for a benzomorphan opiate on acetylcholine receptor-rich membranes from Torpedo electroplaque.
Proc Natl Acad Sci U S A. 1985 Feb;82(3):940-4. doi: 10.1073/pnas.82.3.940.
9
Affinity-labeling of purified acetylcholine receptor from Torpedo californica.加州电鳐纯化乙酰胆碱受体的亲和标记
Biochem Biophys Res Commun. 1974 Dec 11;61(3):997-1003. doi: 10.1016/0006-291x(74)90254-x.
10
Reconstitution of a functional acetylcholine regulator under defined conditions.在特定条件下重建功能性乙酰胆碱调节剂。
FEBS Lett. 1979 Sep 1;105(1):181-7. doi: 10.1016/0014-5793(79)80913-8.

引用本文的文献

1
Sequential purification and characterization of Torpedo californica nAChR-DC supplemented with CHS for high-resolution crystallization studies.依次用经胆固醇亲和分离柱（CHS）补充的加利福尼亚州美洲电鳐 nAChR-DC 进行纯化和鉴定，以用于高分辨率结晶研究。
Anal Biochem. 2020 Dec 1;610:113887. doi: 10.1016/j.ab.2020.113887. Epub 2020 Aug 4.
2
Discovery of the First Neurotransmitter Receptor: The Acetylcholine Nicotinic Receptor.发现第一种神经递质受体：乙酰胆碱烟碱受体。
Biomolecules. 2020 Apr 3;10(4):547. doi: 10.3390/biom10040547.
3
The nicotinic acetylcholine receptor: the founding father of the pentameric ligand-gated ion channel superfamily.
烟碱型乙酰胆碱受体：五聚体配体门控离子通道超家族的奠基人。
J Biol Chem. 2012 Nov 23;287(48):40207-15. doi: 10.1074/jbc.R112.407668. Epub 2012 Oct 4.
4
High affinity binding of alpha-bungarotoxin to the purified alpha-subunit and to its 27,000-dalton proteolytic peptide from Torpedo marmorata acetylcholine receptor. Requirement for sodium dodecyl sulfate.α-银环蛇毒素与纯化的α亚基及其来自电鳐乙酰胆碱受体的27000道尔顿蛋白水解肽的高亲和力结合。对十二烷基硫酸钠的需求。
EMBO J. 1983;2(3):381-7. doi: 10.1002/j.1460-2075.1983.tb01434.x.
5
Analysis of cyclic and acyclic nicotinic cholinergic agonists using radioligand binding, single channel recording, and nuclear magnetic resonance spectroscopy.使用放射性配体结合、单通道记录和核磁共振光谱法对环状和非环状烟碱型胆碱能激动剂进行分析。
Biophys J. 1993 Feb;64(2):325-38. doi: 10.1016/S0006-3495(93)81373-0.
6
The tyrosine phosphorylation site of the acetylcholine receptor beta subunit is located in a highly immunogenic epitope implicated in channel function: antibody probes for beta subunit phosphorylation and function.乙酰胆碱受体β亚基的酪氨酸磷酸化位点位于一个与通道功能相关的高度免疫原性表位：β亚基磷酸化及功能的抗体探针。
EMBO J. 1993 Dec 15;12(13):5141-9. doi: 10.1002/j.1460-2075.1993.tb06209.x.
7
Structural models of the nicotinic acetylcholine receptor and its toxin-binding sites.烟碱型乙酰胆碱受体及其毒素结合位点的结构模型。
Cell Mol Neurobiol. 1981 Sep;1(3):231-58. doi: 10.1007/BF00710680.
8
Change in state of phosphorylation of acetylcholine receptor during maturation of the electromotor synapse in Torpedo marmorata electric organ.斑纹电鳐电器官中电运动突触成熟过程中乙酰胆碱受体磷酸化状态的变化。
Proc Natl Acad Sci U S A. 1981 Jul;78(7):4430-4. doi: 10.1073/pnas.78.7.4430.
9
Ultraviolet light-induced labeling by noncompetitive blockers of the acetylcholine receptor from Torpedo marmorata.用非竞争性阻滞剂对斑纹电鳐乙酰胆碱受体进行紫外线诱导标记。
Proc Natl Acad Sci U S A. 1981 Jun;78(6):3925-9. doi: 10.1073/pnas.78.6.3925.
10
Identification of a cDNA clone coding for the acetylcholine binding subunit of Torpedo marmorata acetylcholine receptor.编码斑纹电鳐乙酰胆碱受体乙酰胆碱结合亚基的cDNA克隆的鉴定。
EMBO J. 1982;1(6):713-7. doi: 10.1002/j.1460-2075.1982.tb01235.x.