补骨脂素加紫外线A照射疗法（PUVA疗法）后皮肤的弹性组织变化
Elastic tissue changes in skin following PUVA therapy.
作者信息
Zelickson A S, Mottaz J H, Zelickson B D, Muller S A
出版信息
J Am Acad Dermatol. 1980 Aug;3(2):186-92. doi: 10.1016/s0190-9622(80)80258-1.
PMID:6893335
Abstract
Treatment of psoriasis with psoralens and high-intensity long-wave ultraviolet light (PUVA) produces changes in the ultrastructure of elastic tissue in skin. Early alterations consist of a loss of elastin followed by a breakdown of the microfibrils and subsequent fragmentation of the elastic fiber. Tissue examined 15 months after treatment was stopped still showed marked ultrastructural changes in the elastic fibers.
摘要
用补骨脂素和高强度长波紫外线（PUVA）治疗银屑病会使皮肤弹性组织的超微结构发生变化。早期改变包括弹性蛋白的丧失，随后是微原纤维的分解以及弹性纤维的碎片化。在停止治疗15个月后检查的组织中，弹性纤维仍显示出明显的超微结构变化。
Zotero 插件