甲状腺疾病中的血清肌红蛋白。
Serum myoglobin in thyroid disease.
作者信息
Karlsson F A, Dahlberg P A, Venge P, Roxin L E
出版信息
Acta Endocrinol (Copenh). 1980 Jun;94(2):184-7. doi: 10.1530/acta.0.0940184.
Serum myoglobin levels were measured longitudinally in patients undergoing therapy because of various thyroid disorders. Elevated myoglobin values - 72.6 (58.7-89.7) micrograms/l (mean +/- SEM) were found in group of hypothyroid subjects. The degree of myoglobin increase seemed related to the severity of hypothyroidism. When rendered euthyroid the myoglobin levels of these patients were normalized - 41.0 (37.3-45.1) micrograms/l. In patients with hyperthyroidism, due to Graves' disease or subacute thyroiditis (de Quervain), only minor changes of myoglobin values within the reference range of health subjects, were measured. This suggests that mechanisms not affecting myoglobin release are responsible for the muscular weakness of thyrotoxic patients.
对因各种甲状腺疾病接受治疗的患者进行了血清肌红蛋白水平的纵向测量。在甲状腺功能减退组中发现肌红蛋白值升高，为72.6（58.7 - 89.7）微克/升（均值±标准误）。肌红蛋白升高的程度似乎与甲状腺功能减退的严重程度相关。当这些患者甲状腺功能恢复正常时，其肌红蛋白水平恢复正常，为41.0（37.3 - 45.1）微克/升。在患有甲状腺功能亢进症的患者中，无论是格雷夫斯病还是亚急性甲状腺炎（德·克萨韦恩甲状腺炎），仅测量到肌红蛋白值在健康受试者参考范围内有轻微变化。这表明不影响肌红蛋白释放的机制是甲状腺毒症患者肌肉无力的原因。
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