9-（5-羧基戊基氨基）吖啶。一种用于电鳗乙酰胆碱酯酶的亲和吸附配体。
9-(5-Carboxypentylamino)-acridine. An affinity adsorbent ligand for Electrophorus acetylcholinesterase.
作者信息
Brooks A S, Tiller G E, Struve W G
出版信息
Biochim Biophys Acta. 1980 Oct;615(2):354-9. doi: 10.1016/0005-2744(80)90502-1.
PMID:6893418
Abstract
We have developed a simple method for the synthesis of the ligand 9-(5-carboxypentylamino)-acridine and the resulting affinity adsorbent using Sepharose CL-4B. This affinity adsorbent is efficient and specific for purification acetylcholinesterase (acetylcholine acetylhydrolase, EC 3.1.1.7) from Electrophorus electricus electric organ.
摘要
我们已经开发出一种简单的方法，用于合成配体9-(5-羧基戊基氨基)-吖啶，并使用琼脂糖凝胶CL-4B制备所得的亲和吸附剂。这种亲和吸附剂对于从电鳗电器官中纯化乙酰胆碱酯酶（乙酰胆碱乙酰水解酶，EC 3.1.1.7）高效且具有特异性。
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