伊维菌素，一种新型广谱抗寄生虫药。
Ivermectin, a new broad-spectrum antiparasitic agent.
作者信息
Chabala J C, Mrozik H, Tolman R L, Eskola P, Lusi A, Peterson L H, Woods M F, Fisher M H, Campbell W C, Egerton J R, Ostlind D A
出版信息
J Med Chem. 1980 Oct;23(10):1134-6. doi: 10.1021/jm00184a014.
PMID:6893469
Abstract
22,23-Dihydroavermectin B1, ivermectin, derived from avermectin B1 by selective hydrogenation using Wilkinson's homogenous catalyst [Ph3P)3RhCl], was shown to be a highly effective drug for the treatment of a wide variety of metazoan parasitic diseases in animals.
摘要
22,23-二氢阿维菌素B1（伊维菌素）是通过使用威尔金森均相催化剂[三（三苯基膦）氯化铑（Ph3P)3RhCl]对阿维菌素B1进行选择性氢化而得到的，它被证明是一种治疗动物多种后生动物寄生虫病的高效药物。
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