Banna H B
Histochem J. 1980 Mar;12(2):139-44. doi: 10.1007/BF01024544.
The histochemistry of five dehydrogenases, namely isocitrate, succinate and lactate dehydrogenases and NADH and NADPH diaphorases were studied in the tissues of the schistosome vector snail, Bulinus truncatus, before and after treatment with the molluscicide Frescon. Isocitrate and succinate dehydrogenases showed their strongest activity in the respiratory epithelia, while lactate dehydrogenase showed a high level of activity in the tissues that are known to be capable of glycolysis. Following the administration of Frescon, a marked loss in the activity of isocitrate dehydrogenase and NADPH diaphorase occurred. It is postulated that the molluscicide toxin may interfere with cellular respiration, especially in the exposed areas of the body.
在使用杀螺剂Frescon处理之前和之后，对血吸虫中间宿主截形小泡螺（Bulinus truncatus）的组织中五种脱氢酶，即异柠檬酸脱氢酶、琥珀酸脱氢酶和乳酸脱氢酶以及NADH和NADPH黄递酶的组织化学进行了研究。异柠檬酸脱氢酶和琥珀酸脱氢酶在呼吸上皮中表现出最强的活性，而乳酸脱氢酶在已知能够进行糖酵解的组织中表现出高水平的活性。施用Frescon后，异柠檬酸脱氢酶和NADPH黄递酶的活性明显丧失。据推测，杀螺剂毒素可能会干扰细胞呼吸，尤其是在身体暴露部位。
