Karmazsin L, Lakatos L, Balla G, Makay A, Hatvani L
Acta Paediatr Acad Sci Hung. 1980;21(2-3):131-8.
Superoxide dismutase activity of alveolar macrophages, lung, liver, retina and choroid has been studied in rats and rabbits exposed to oxygen at high concentration by itself and in combination with D-penicillamine. Prolonged hyperoxia caused an increase in superoxide dismutase activity while D-penicillamine was found to inhibit the inductive effect of oxygen. It is assumed that the antioxidative effect of D-penicillamine makes it unnecessary to augment the production of superoxide dismutase.
在单独暴露于高浓度氧气以及同时联合D-青霉胺的大鼠和家兔中，研究了肺泡巨噬细胞、肺、肝脏、视网膜和脉络膜的超氧化物歧化酶活性。长时间高氧导致超氧化物歧化酶活性增加，而发现D-青霉胺可抑制氧气的诱导作用。据推测，D-青霉胺的抗氧化作用使得无需增加超氧化物歧化酶的产生。
