Bauer F C, Mirra J M, Urist M R
Arch Pathol Lab Med. 1981 Jun;105(6):322-4.
Fresh specimens from two cases of Ewing's sarcoma were implanted in thigh muscles of nude athymic mice. Ewing's sarcomas induced differentiation of mouse-derived new bone in the same fashion as osteogenic sarcomas and chondrosarcomas. Control transplants of eight primary nonosseous and metastatic tumors did not induce bone formation. The osteoinductive action of Ewing's sarcoma is submitted as evidence of its origin from an osteogenic cell rather than from a hematopoietic cell line.
将两例尤因肉瘤的新鲜标本植入无胸腺裸鼠的大腿肌肉中。尤因肉瘤诱导小鼠来源的新骨分化，其方式与骨肉瘤和软骨肉瘤相同。八例原发性非骨性和转移性肿瘤的对照移植未诱导骨形成。尤因肉瘤的骨诱导作用被视为其起源于成骨细胞而非造血细胞系的证据。
