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A phase II trial of m-AMSA in head and neck cancer.

作者信息

Forastiere A A, Young C W, Wittes R E

出版信息

Cancer Chemother Pharmacol. 1981;6(2):145-6. doi: 10.1007/BF00262333.

DOI:10.1007/BF00262333
PMID:6895486
Abstract

Twenty patients with advanced epidermoid carcinoma from primary sites in the head and neck region received adequate trials of therapy with m-AMSA, at starting doses of 90 or 120 mg/m2. Despite the good median performance status of the group (median 80) and the fact that 50% of the patients had received no prior chemotherapy, only one minor response was achieved. AMSA appears to have no useful activity in this dose and schedule in patients with epidermoid head and neck cancer.

摘要

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本文引用的文献

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Phase II. Evaluation of 4'-(9-acridinylamino)-methanesulfon-m-anisidide (AMSA) in patients with advanced sarcoma.第二阶段:对晚期肉瘤患者使用4'-(9-吖啶基氨基)-甲磺酰间茴香胺(AMSA)的评估。
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