Pupillary analyses in Graves' disease.

Using electronic videopupillography, the direct pupillary response to light and edge light pupillary oscillation by slit light stimulus was examined in patients with hyperthyroidism and in controls. Amplitude of constriction, velocities of constriction and dilatation significantly reduced in the patients in pupillary response to light. The pupillary oscillation was also reduced in the amplitude of oscillation as well as in the velocities of dilatation and constriction. These alterations in pupillary response to light correlated only with the triiodothyronine-RSU test. The oscillation correlated with the duration of the disease. The results indicated that the pupil dynamics were abnormal in patients with hyperthyroidism and this can be demonstrated by sensitive pupillography.