Hirsch S A, Saidi P, Hirsch P J
Prim Care. 1980 Jun;7(2):311-6.
Spontaneous deep muscle and joint bleeding is a common characteristic of severe hemophilia, often causing damage to the musculoskeletal system. The development of concentrated replacement factors, however, has made home care programs possible, helped prevent deformity, and improved surgical management.
自发性深部肌肉和关节出血是严重血友病的常见特征，常导致肌肉骨骼系统受损。然而，浓缩替代因子的研发使家庭护理方案成为可能，有助于预防畸形并改善手术治疗。
