Bruns G R, Ablin R J, Guinan P D
J Invest Dermatol. 1978 Sep;71(3):217-8. doi: 10.1111/1523-1747.ep12547283.
Immunoglobulin E levels in the sera of patients with pemphigus (12 with Brazilian pemphigus foliaceus (BPF) and 11 with pemphigus vulgaris (PV)) were determined by means of a solid phase radioimmunoassay. A significant increase in IgE level was observed in BPF patients compared to the level of IgE in PV patients and healthy adults. The implications of an elevated level of IgE with respect to other aberrations of immunologic responsiveness and the suggested infectious etiology of BPF are considered.
采用固相放射免疫测定法测定了天疱疮患者（12例巴西落叶型天疱疮（BPF）患者和11例寻常型天疱疮（PV）患者）血清中的免疫球蛋白E水平。与PV患者和健康成年人的IgE水平相比，BPF患者的IgE水平显著升高。研究了IgE水平升高与免疫反应性其他异常以及BPF可能的感染病因之间的关系。
