Ramanathan V S, Chandra P
Bull Narc. 1980;32(2):49-63.
The thebaine content of the opium collected in the Madhya Pradesh region of India has been estimated and reported to range from 1.5 to 2.0 per cent. A technological process for the recovery of thebaine from the mother liquor remaining after the separation of natural codeine in the Government Opium and Alkaloid Works, Neemuch, has been developed in the laboratory and stepped up to an industrial scale. A method for the recovery to thebaine from the waste slaked-lime residues obtained from crude alkaloid cake mother liquor in the Government Opium and Alkaloid Works at Ghazipur has been worked out and the technical details of the process described. The recovery of thebaine would help to increase the production of codeine, and thebaine can also be used as a raw material for the manufacture of other drugs. Cryptopine has also been recovered from the mother liquor after the separation of thebaine.
据估计，印度中央邦地区采集的鸦片中蒂巴因含量为1.5%至2.0%。在尼穆奇政府鸦片与生物碱工厂，已在实验室研发出从天然可待因分离后剩余母液中回收蒂巴因的工艺流程，并扩大至工业规模。已研究出从加济布尔政府鸦片与生物碱工厂粗生物碱饼母液产生的废熟石灰残渣中回收蒂巴因的方法，并描述了该工艺的技术细节。回收蒂巴因将有助于提高可待因产量，且蒂巴因还可用作制造其他药物的原料。在分离出蒂巴因后的母液中也已回收了隐品碱。
