Lanzer G, Pogglitsch H, Tilz G P
Acta Med Austriaca. 1981;8(1):7-13.
The C3-nephritic-factor is an autoantibody specific against C3-convertases. This IgG-immunoglobulin is particularly found in patients suffering from membranoproliferative glomerulonephritis and causes a complement-activation under elimination of physiological regulator mechanisms. The clinical importance of this factor is discussed.
C3肾炎因子是一种针对C3转化酶的自身抗体。这种IgG免疫球蛋白尤其在患有膜增生性肾小球肾炎的患者中发现,并在消除生理调节机制的情况下引起补体激活。本文讨论了该因子的临床重要性。