Lewis S E, Turchin H A, Wojtowicz T E
J Reprod Fertil. 1978 Jul;53(2):197-202. doi: 10.1530/jrf.0.0530197.
Mice doubly heterozygous for two radiation-induced lethal alleles at the albino locus (C3H and C6H) show partial complementation: they are viable but runted and sterile. In C3H/C6H females oogenesis and mating are normal, but nearly all of their fetuses, even when genotypically normal (+/C3H or +/C6H), fail to survive beyond midgestation. Abnormalities of spermatogenesis, i.e. morphological defects in head condensation and a deficiency in numbers of maturing spermatids, are histologically detectable in the testes of C3H/C6H males. Spermatozoa from the vasa deferentia of such males are predominantly nonviable, immotile, and grossly abnormal in morphology.
在白化病位点（C3H和C6H）因两个辐射诱导的致死等位基因而双杂合的小鼠表现出部分互补：它们是存活的，但发育不良且不育。在C3H/C6H雌性小鼠中，卵子发生和交配正常，但几乎所有胎儿，即使基因型正常（+/C3H或+/C6H），也无法在妊娠中期后存活。在C3H/C6H雄性小鼠的睾丸中，组织学上可检测到精子发生异常，即头部凝聚的形态学缺陷和成熟精子数量不足。来自此类雄性小鼠输精管的精子主要是无活力、不动且形态严重异常的。
