大鼠尿激肽释放酶排泄的机制。
The mechanism of urinary kallikrein excretion in the rat.
作者信息
Martínez Seeber A, Vila S B, Catanzaro O L
出版信息
Clin Sci (Lond). 1982 Aug;63(2):217-8. doi: 10.1042/cs0630217.
PMID:6919474
Abstract
- In male Wistar rats urinary kallikrein excretion was positively correlated with urinary flow and glomerular filtration rate (GFR). 2. Osmotic diuresis produced by a 30% (w/v) glucose solution increased urinary kallikrein, and a positive correlation between this variable and urine flow was observed. No correlation was observed with GFR. 3. The mechanism of urinary kallikrein excretion is interpreted as a wash-out effect of renal kallikrein.
摘要
- 在雄性Wistar大鼠中，尿激肽释放酶排泄与尿流和肾小球滤过率（GFR）呈正相关。2. 30%（w/v）葡萄糖溶液产生的渗透性利尿增加了尿激肽释放酶，并且观察到该变量与尿流之间呈正相关。未观察到与GFR的相关性。3. 尿激肽释放酶排泄的机制被解释为肾激肽释放酶的冲洗效应。
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