Abdullaev A A
Kardiologiia. 1978 Aug;18(8):118-24.
Blood viscosity, platelet and erythrocyte aggregation, venous hematocrit, and blood free fatty acid, fibrinogen, and glucose content were studied in dynamics in 63 patients with paroxysmal disorders of cardiac rhythm. During an attack of arrhythmia, the viscosity of blood, aggregation of erythrocytes, and the concentration of free fatty acids and glucose in blood were significantly increased, while the degree and rate of the reversibility of platelet aggregation were reduced. The reversibility of platelet aggregation increased after the attacks had been arrested with drugs and slightly decreased after electroimpulsive therapy. This may underlie the development of thromboembolic complications and postconversion arrhythmias after electropuls therapy. Increase in the rate of erythrocyte aggregation immediately after the arrest of an attack by an electric discharge was also revealed. The authors believe that deterioration of the blood rheologic properties is one of the pathogenetic mechanisms of the development of cardiac arrhythmias.
对63例阵发性心律失常患者的血液粘度、血小板和红细胞聚集性、静脉血细胞比容以及血液游离脂肪酸、纤维蛋白原和葡萄糖含量进行了动态研究。在心律失常发作期间，血液粘度、红细胞聚集性以及血液中游离脂肪酸和葡萄糖的浓度显著增加，而血小板聚集的可逆程度和速率降低。在用药物控制发作后，血小板聚集的可逆性增加，而在电脉冲治疗后略有下降。这可能是电脉冲治疗后血栓栓塞并发症和复律后心律失常发生的原因。还发现放电终止发作后红细胞聚集速率立即增加。作者认为血液流变学性质的恶化是心律失常发生的发病机制之一。
