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[在宇宙-690生物卫星上暴露的大鼠的精子发生状态]

[State of spermatogenesis in rats exposed on the Cosmos-690 biosatellite].

作者信息

Plakhuta-Plakutina G I

出版信息

Kosm Biol Aviakosm Med. 1978 Sep-Oct;12(5):26-31.

PMID:692066
Abstract

A morphological examination of sex glands of 30 male rats flown aboard the biosatellite Cosmos-690 was carried out on the 1st-2nd and 26-27th postflight days. A combined exposure to the 20-day space flight and prolonged gamma-irradliation with doses of 220, 800 and 955 rad brought about a significant decrease of the weight of testes, postradiation death of spermatogonia and essential structural changes in the spermatogenic epithelium whose level depended on the radiation dose and the postirradiation time. A comparison of weights and histologies of testes from the flight and synchronous rats did not reveal a modifying effect of weightlessness since no statistically significant differences in the testicular weight, quantitative assay of the occurrence of individual elements of the spermatogenic epithelium and time of manifestation of reparative processes were observed.

摘要

在飞行后第1至2天和第26至27天,对搭载生物卫星“宇宙-690”号飞行的30只雄性大鼠的性腺进行了形态学检查。20天的太空飞行与剂量为220、800和955拉德的长期伽马辐射联合作用,导致睾丸重量显著下降,精原细胞辐射后死亡,生精上皮出现实质性结构变化,其变化程度取决于辐射剂量和辐射后时间。对飞行大鼠和同步对照大鼠的睾丸重量和组织学进行比较,未发现失重的调节作用,因为在睾丸重量、生精上皮各单个成分出现情况的定量分析以及修复过程表现时间方面,均未观察到统计学上的显著差异。

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