Dietl J, Buchholz F, Semm K
Geburtshilfe Frauenheilkd. 1982 Jun;42(6):472-5. doi: 10.1055/s-2008-1036799.
65 microcarcinomas and 189 Ca. in situ-cases were diagnosed by cone biopsy in the Department of Gynaecology and Obstetrics of the University in Kiel in the periods 1973-1976 and 1977-1980. During the first period the haemostasis of the conization crater was obtained by the conventional techniques. In 38% (microcarcinoma) and 30% (Ca. in situ) of the cases the excised uterus was free of pathological epithelium. Since 1977 we have used simple coagulation of the wound area, with endocoagulation-technique according to Semm. In the second group (1977-1980), 73% (microcarcinoma) and 45% (Ca. in situ) were histologically normal, and only one case showed remaining microcarcinoma in the excised uterus. In individual cases--such as during pregnancy or where the patient still desires to have children--the Ca. in situ with not free margins, can be treated simply with a secondary coagulation of the wound crater.
1973 - 1976年以及1977 - 1980年期间，基尔大学妇产科通过锥形活检诊断出65例微癌和189例原位癌病例。在第一个时期，锥形切除创口的止血采用传统技术。在38%（微癌）和30%（原位癌）的病例中，切除的子宫没有病理上皮。自1977年以来，我们采用根据Semm的内膜凝固技术对伤口区域进行简单凝固。在第二组（1977 - 1980年）中，73%（微癌）和45%（原位癌）在组织学上是正常的，只有1例在切除的子宫中显示有残留微癌。在个别情况下，如怀孕期间或患者仍希望生育时，对于切缘不净的原位癌，可通过对伤口创口进行二次凝固来简单处理。
