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可活动舌部及口底的“局限性”癌——一种常被误诊和治疗不足的病变。

"Localized" carcinoma of the mobile tongue and floor of the mouth--a lesion frequently misjudged and undertreated.

作者信息

McColl H A, Horwood J

出版信息

J Surg Oncol. 1978;10(4):337-45. doi: 10.1002/jso.2930100408.

Abstract

A retrospective study of 74 cases of cancer of the mobile tongue and floor of the mouth, diagnosed between 1949 and 1975, with a two-year minimum follow-up was undertaken. The lesions were TNM staged, stages I and II accounting for 56 cases (76%) and stages III and IV accounting for 18 cases (24%). The analysis was restricted to the "localized" stage I and stage II lesions. In this group failure occurred in 31 patients, or 55% of the group. Failure at the primary site accounted for 10 of the failures, failure at both primary and cervical lymph nodes accounted for 14, and failure at cervical lymph nodes only accounted for 7 of the failures. The treatment for these "localized" lesions was then analyzed for modality, adequacy, presence or absence of planning failure, and survival. The results indicate the lethal nature of this lesion when inadequately treated and strongly suggest more extensive use of prophylactic therapy to the cervical lymph nodes.

摘要

对1949年至1975年间诊断出的74例活动期舌癌和口底癌病例进行了回顾性研究,至少随访两年。病变按TNM分期,I期和II期占56例(76%),III期和IV期占18例(24%)。分析仅限于“局限性”的I期和II期病变。该组中有31例患者出现失败,占该组的55%。原发部位失败占失败病例的10例,原发部位和颈部淋巴结均失败占14例,仅颈部淋巴结失败占失败病例的7例。然后对这些“局限性”病变的治疗方式、充分性、是否存在计划失败以及生存率进行了分析。结果表明,治疗不充分时该病变具有致命性,并强烈建议更广泛地对颈部淋巴结进行预防性治疗。

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