Dabeva M D, Dudov K P
Biochem J. 1982 Apr 15;204(1):179-83. doi: 10.1042/bj2040179.
A quantitative analysis of the nuclear pre-rRNA (precursor to rRNA) and rRNA in normal and 12h-regenerating rat liver was carried out, and the absolute amounts of the identified pre-rRNA and rRNA species in the nucleolus and nucleoplasm were determined. Characteristic changes in the pre-rRNA and rRNA pool sizes in regenerating liver are found which reveal alternations in both pre-rRNA processing and nucleocytoplasmic transition of ribosomes.
对正常大鼠肝脏和再生12小时的大鼠肝脏中的核前体rRNA(rRNA的前体)和rRNA进行了定量分析,并测定了核仁与核质中已鉴定的前体rRNA和rRNA种类的绝对量。发现再生肝脏中前体rRNA和rRNA库大小的特征性变化,这些变化揭示了前体rRNA加工和核糖体核质转运的改变。