Schramm W, Schaarschmidt K, Schmidtler F, Schildberg F W
MMW Munch Med Wochenschr. 1977 May 20;119(20):690-4.
By reference to clinically established risk factors, patients with an increased tendency to disturbances of wound healing were selected and investigated hemostasiologically in a prospective study. Abdominal wound dehiscence occurred postoperatively in 12 of the 28 patients selected clinically as being endangered. In all collectives the Factor XIII concentration fell postoperatively and remained low in the patients with a wound rupture, whereas it rose significantly in patients with undisturbed wound healing. Connections between hemostasis and wound healing are discussed.
通过参考临床已确定的风险因素,选择有伤口愈合障碍倾向增加的患者,并在前瞻性研究中对其进行血液止血学调查。在临床上被选为有风险的28例患者中,有12例术后发生腹部伤口裂开。在所有组中,凝血因子XIII浓度术后下降,伤口裂开的患者中该浓度持续较低,而伤口愈合未受影响的患者中该浓度显著上升。文中讨论了止血与伤口愈合之间的关系。