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极低出生体重儿的支气管肺发育不良

[Bronchopulmonary dysplasia in very low birth weight infants].

作者信息

Pezzani F M, Montali S, Lazzerini M, Bini F

出版信息

Pediatr Med Chir. 1982 Sep-Oct;4(5):497-500.

PMID:6927345
Abstract

The reported incidence of Bronchopulmonary dysplasia (BPD) varies from 5% to 68%. The different criteria used to define BPD are responsable for these discrepancies: some Authors include only patients with a clinical and radiological picture that fits the stage IV, as originally described by Northway, others use a more liberal approach and include all patients with manifestations of chronic pulmonary disease. We observed BPD in 12 of 22 (54%) survivors infants of very low birth weight (mean 1115 gm) and gestational age (mean 29,2 weeks). The infants were all born between November 1979 and March 1981. According to Ehrenkranz et al., we classified the radiological findings as severe, moderate and mild. We believe that the etiology of BPD in very low birth weight infants is multifactorial. However, pulmonary oxygen toxicity and immaturity are the most important causes.

摘要

据报道,支气管肺发育不良(BPD)的发病率在5%至68%之间。用于定义BPD的不同标准导致了这些差异:一些作者仅将具有符合Northway最初描述的IV期临床和放射学表现的患者纳入,另一些作者则采用更宽松的方法,将所有患有慢性肺部疾病表现的患者纳入。我们在22例极低出生体重(平均1115克)和胎龄(平均29.2周)的存活婴儿中观察到12例(54%)患有BPD。这些婴儿均在1979年11月至1981年3月之间出生。根据Ehrenkranz等人的方法,我们将放射学表现分为重度、中度和轻度。我们认为,极低出生体重婴儿BPD的病因是多因素的。然而,肺部氧中毒和肺不成熟是最重要的原因。

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